2403598-42-3

2403598-42-3 structure

Name: HPK1-IN-18
Chemical Name: HPK1-IN-18
CAS Number: 2403598-42-3
Molecular Formula: C₂₄H₂₄N₄
Molecular Weight: 368.47
Catalog: Signaling Pathways MAPK/ERK Pathway MAP4K
Create Date: 2022-04-07 19:25:29
Modify Date: 2025-08-29 14:35:28
HPK1-IN-18 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-18 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2019238067A1, compound 1)[1].

Name	HPK1-IN-18

Description	HPK1-IN-18 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-18 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2019238067A1, compound 1)[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> MAP4K Research Areas >> Cancer Research Areas >> Inflammation/Immunology
References	[1]. Jing Li, et al. Pyrrolo [2, 3-b] pyridines or pyrrolo [2, 3-b] pyrazines as hpk1 inhibitor and the use thereof. Patent WO2019238067A1.

Molecular Formula	C₂₄H₂₄N₄
Molecular Weight	368.47