2353522-15-1

2353522-15-1 structure

Name: Paltimatrectinib
Chemical Name: Paltimatrectinib
CAS Number: 2353522-15-1
Molecular Formula: C₂₀H₁₅F₅N₆
Molecular Weight: 434.37
Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
Create Date: 2022-03-23 07:55:00
Modify Date: 2024-01-10 18:51:45
Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases[1].

Name	Paltimatrectinib

Description	Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor
Target	TrkA
References	[1]. Kollol Pal, et al. 5-(2-(2,5-difluorophenyl)pyrrolidin-1 -yl)-3-(1h-pyrazol-1-yl)pyrazolo[1,5-a]pyrimidine derivatives and related compounds as trk kinase inhibitors for treating cancer. WO2019118584A1.

Molecular Formula	C₂₀H₁₅F₅N₆
Molecular Weight	434.37