1322598-09-3

1322598-09-3 structure

Name: CATPB
Chemical Name: CATPB
CAS Number: 1322598-09-3
Molecular Formula: C₁₉H₁₇ClF₃NO₃
Molecular Weight: 399.79
Catalog: Research Areas Metabolic Disease
Create Date: 2022-03-26 17:13:16
Modify Date: 2025-09-18 20:09:55
CATPB is a potent, selective free fatty acid receptor 2 (FFA2R/GPR43) antagonist[1].

Name	CATPB
Synonyms	(3S)-3-{(Z)-[2-(3-Chlorophenyl)-1-hydroxyethylidene]amino}-4-[4-(trifluoromethyl)phenyl]butanoic acid (S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoic acid CATPB Benzenebutanoic acid, β-[[(1Z)-2-(3-chlorophenyl)-1-hydroxyethylidene]amino]-4-(trifluoromethyl)-, (βS)-

Description	CATPB is a potent, selective free fatty acid receptor 2 (FFA2R/GPR43) antagonist[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	FFA2R(GPR43)[1]
In Vitro	CATPB inhibits the transient rise in intracellular Ca2+ induced in neutrophils by acetate or Cmp1 (FFAR2 agonist)[1]. CATPB inhibits Cmp1-induced NADPH oxidase activity[1].
References	[1]. Lena Björkman, et al. The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment. Mol Cell Biol. 2016 Sep 26;36(20):2583-95.