DC Chemicals Limited
China
Product Name: MrgprX2 antagonist-5
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2527815-74-1

2527815-74-1 structure

2527815-74-1 structure

Name: MrgprX2 antagonist-5
Chemical Name: MrgprX2 antagonist-5
CAS Number: 2527815-74-1
Molecular Formula: C₁₉H₁₃ClF₂N₄O₂S
Molecular Weight: 434.85
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-03-12 18:57:56
Modify Date: 2024-01-20 12:25:44
MrgprX2 antagonist-5 is an MrgprX2 antagonist extracted from patent WO2020223255A1, example 16. MrgprX2 antagonist-5 can be used for the research of inflammatory disorders of the skin[1].

Name	MrgprX2 antagonist-5

Description	MrgprX2 antagonist-5 is an MrgprX2 antagonist extracted from patent WO2020223255A1, example 16. MrgprX2 antagonist-5 can be used for the research of inflammatory disorders of the skin[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	MrgprX2[1]
In Vitro	MRGPRX2, a member of the Mas-related gene family, was found to be expressed in sensory neurons, mast cells and, most recently, in keratinocytes. MRGPRX2 mRNA is present in adipose tissue, esophagus, urinary bladder, lungs with the highest levels found in skin. Activation of MRGPRX2 leads to mast cell degranulation with subsequent pseudo-allergic reactions[2].
References	[1]. BIGI S, et, al. 3-amino-4h-benzo[e][1,2,4]thiadiazine 1,1-dioxide derivatives as inhibitors of mrgx2. WO2020223255A1. [2]. Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027.

Molecular Formula	C₁₉H₁₃ClF₂N₄O₂S
Molecular Weight	434.85