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1231737-88-4

1231737-88-4 structure
1231737-88-4 structure
  • Name: Teprasiran
  • Chemical Name: Teprasiran
  • CAS Number: 1231737-88-4
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Signaling Pathways Apoptosis MDM-2/p53
  • Create Date: 2021-12-19 16:34:58
  • Modify Date: 2024-01-11 11:25:31
  • Teprasiran (QPI-1002) is a small interfering RNA that temporarily inhibits p53-mediated cell death that underlies acute kidney injury (AKI)[1].

Name Teprasiran
Description Teprasiran (QPI-1002) is a small interfering RNA that temporarily inhibits p53-mediated cell death that underlies acute kidney injury (AKI)[1].
Related Catalog
In Vitro Teprasiran is a synthetic, chemically stabilized small interfering RNA (siRNA) acting through RNA interference, which temporarily inhibits p53 expression for ≈48 to 72 hours[1].
References

[1]. Matthias Thielmann, et al. Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study. Circulation. 2021;144:1133-1144.

No Any Chemical & Physical Properties
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