Shanghai Nianxing Industrial Co., Ltd
China
Product Name: RG-101
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: RG-101
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1929655-04-8

1929655-04-8 structure

1929655-04-8 structure

Name: RG-101
Chemical Name: RG-101
CAS Number: 1929655-04-8
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Epigenetics MicroRNA
Create Date: 2021-12-26 19:55:10
Modify Date: 2025-08-25 19:56:54
RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication[1].

Name	RG-101

Description	RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication[1].
Related Catalog	Signaling Pathways >> Epigenetics >> MicroRNA Research Areas >> Infection
In Vitro	RG-101 is a mixed chemistry phosphorothioate oligonucleotide inhibitor of miR-122 that is linked to a multivalent N-acetylgalactosamine carbohydrate structure designed to enhance uptake of the oligonucleotide by hepatocytes through binding to the asialoglycoprotein receptor on hepatocytes[1].
References	[1]. Meike H van der Ree, et al. Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial. Lancet. 2017 Feb 18;389(10070):709-717.

No Any Chemical & Physical Properties

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