1639324-58-5
1639324-58-5 structure
- Name: Inclisiran
- Chemical Name: Inclisiran
- CAS Number: 1639324-58-5
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Ser/Thr Protease
- Create Date: 2021-12-20 11:15:37
- Modify Date: 2024-01-03 19:32:19
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Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran can be used for hyperlipidemia and cardiovascular disease (CVD) research[1].
| Name | Inclisiran |
|---|
| Description | Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran can be used for hyperlipidemia and cardiovascular disease (CVD) research[1]. |
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| Related Catalog | |
| In Vitro | Inclisiran is a double-stranded small RNA molecule that works by blocking the transcription of proprotein convertase subtilisin kexin 9 (PCSK-9), leading to a reduction of PCSK-9 levels in the hepatocytes, resulting in an increased expression of low-density lipoprotein (LDL) receptors in the hepatocyte membrane and, as a consequence, it reduces the circulating levels of LDL cholesterol (LDL-C)[1]. |
| References |
| No Any Chemical & Physical Properties |