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2055496-11-0

2055496-11-0 structure
2055496-11-0 structure
  • Name: Cedirogant
  • Chemical Name: Cedirogant
  • CAS Number: 2055496-11-0
  • Molecular Formula: C24H20Cl3F3N2O3
  • Molecular Weight: 547.78
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease ROR
  • Create Date: 2021-12-22 14:17:24
  • Modify Date: 2024-09-17 09:49:39
  • Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research[1][2].

Name Cedirogant
Description Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research[1][2].
Related Catalog
Target

RORγt[1]

In Vitro The transcription factor retinoic acid-related orphan receptor gamma t (RORγt) has been identified as the master regulator of TH17 cell differentiation and IL-17/22 production and is therefore an attractive target for the treatment of inflammatory diseases. Cedirogant (ABBV-157) has the potential for chronic plaque psoriasis research[1].
References

[1]. Elena Campione, et al. Experimental Pharmacological Management of Psoriasis. J Exp Pharmacol. 2021 Jul 26;13:725-737.

[2]. Christian Gege. Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently? Expert Opin Drug Discov. 2021 Jul 7;1-19.

Molecular Formula C24H20Cl3F3N2O3
Molecular Weight 547.78