884905-07-1

884905-07-1 structure

Name: Larsucosterol
Chemical Name: (3β)-25-Hydroxycholest-5-en-3-yl hydrogen sulfate
CAS Number: 884905-07-1
Molecular Formula: C₂₇H₄₆O₅S
Molecular Weight: 482.72
Catalog: Research Areas Metabolic Disease
Create Date: 2022-03-21 23:27:56
Modify Date: 2023-02-25 11:31:41
Larsucosterol is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis[1][2].

Name	(3β)-25-Hydroxycholest-5-en-3-yl hydrogen sulfate
Synonyms	(3β)-25-Hydroxycholest-5-en-3-yl hydrogen sulfate Cholest-5-ene-3,25-diol, 3-(hydrogen sulfate), (3β)-

Description	Larsucosterol is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Ren S, Hylemon P, Zhang ZP, Rodriguez-Agudo D, Marques D, Li X, Zhou H, Gil G, Pandak WM. Identification of a novel sulfonated oxysterol, 5-cholesten-3beta,25-diol 3-sulfonate, in hepatocyte nuclei and mitochondria. J Lipid Res. 2006 May;47(5):1081-90. doi: 10.1194/jlr.M600019-JLR200. Epub 2006 Feb 27. PMID: 16505492. [2]. Wang Y, Li X, Ren S. Cholesterol Metabolites 25-Hydroxycholesterol and 25-Hydroxycholesterol 3-Sulfate Are Potent Paired Regulators: From Discovery to Clinical Usage. Metabolites. 2020 Dec 25;11(1):9.