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859217-52-0

859217-52-0 structure
859217-52-0 structure
  • Name: Milategrast
  • Chemical Name: 1-(Cyclopropylmethyl)-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine
  • CAS Number: 859217-52-0
  • Molecular Formula: C24H38N2
  • Molecular Weight: 354.57
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2022-01-06 19:10:28
  • Modify Date: 2025-08-25 21:04:04
  • Milategrast is useful as cell adhesion inhibitor or cell infiltration inhibitor. Milategrast in vitro inhibites the adhesion of Jurkat cells to human fibronectin with an IC50 of <5 μM[1].

Name 1-(Cyclopropylmethyl)-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine
Synonyms 1-(Cyclopropylmethyl)-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine
Piperazine, 1-(cyclopropylmethyl)-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]-
Description Milategrast is useful as cell adhesion inhibitor or cell infiltration inhibitor. Milategrast in vitro inhibites the adhesion of Jurkat cells to human fibronectin with an IC50 of <5 μM[1].
Related Catalog
References

[1]. Kotake, Makoto; Yoneda, Naoki; Osada, Katsunobu.Preparation of various crystal forms and salts of 1-cyclopropylmethyl-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine for treating or preventing various inflammatory diseases and autoimmune diseases.WO2006068058A1

Density 1.0±0.1 g/cm3
Boiling Point 441.4±45.0 °C at 760 mmHg
Molecular Formula C24H38N2
Molecular Weight 354.57
Flash Point 194.6±16.5 °C
Exact Mass 354.303497
LogP 7.28
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.533
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