610786-69-1

610786-69-1 structure

Name: (S,E)-Ethyl 2,5-Dimethyl-4-(Methylamino)Hex-2-Enoate Hydrochloride
Chemical Name: 2-Hexenoic acid, 2,5-dimethyl-4-(methylamino)-, ethyl ester, hydrochloride, (2E,4S)-
CAS Number: 610786-69-1
Molecular Formula: C₁₁H₂₂ClNO₂
Molecular Weight: 235.75
Catalog: Research Areas Cancer
Create Date: 2022-02-06 11:10:01
Modify Date: 2023-01-16 09:03:30
Taltobulin intermediate-3 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].

Name	2-Hexenoic acid, 2,5-dimethyl-4-(methylamino)-, ethyl ester, hydrochloride, (2E,4S)-
Synonyms	Ethyl (2E,4S)-2,5-dimethyl-4-(methylamino)-2-hexenoate hydrochloride (1:1) MFCD29472351 2-Hexenoic acid, 2,5-dimethyl-4-(methylamino)-, ethyl ester, (2E,4S)-, hydrochloride (1:1)

Description	Taltobulin intermediate-3 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.