34221-41-5

34221-41-5 structure

Name: Echinatin
Chemical Name: (E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
CAS Number: 34221-41-5
Molecular Formula: C₁₆H₁₄O₄
Molecular Weight: 270.280
Catalog: Natural product Chalcone
Create Date: 2018-09-23 17:52:59
Modify Date: 2025-08-23 18:15:09
Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects. Echinatin may undergo an electron transfer (ET) and a proton transfer (PT) to cause the antioxidant action in aqueous solution[1]. Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat[2].

Name	(E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
Synonyms	Echinatin Retrochalcone (2E)-3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one Echinantin 2-Propen-1-one, 3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)- 2-methoxy-4,4'-dihydroxychalcone (2E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one loureirin C (E)-4,4'-Dihydroxy-2-methoxychalcone 4',4-dihydroxy-2-methoxychalcone

Description	Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects. Echinatin may undergo an electron transfer (ET) and a proton transfer (PT) to cause the antioxidant action in aqueous solution[1]. Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Liang M, et al. Antioxidant Mechanisms of Echinatin and Licochalcone A. Molecules. 2018 Dec 20;24(1). [2]. Inoue B, et al. The effects of echinatin and its related compounds on the mitochondrial energy transfer reaction. J Toxicol Sci. 1982 Nov;7(4):245-54.

HS Code	2914509090

18278-34-7

99-93-4

34221-41-5

Literature: Achenbach, Hans; Stoecker, Markus; Constenla, Manuel A. Phytochemistry (Elsevier), 1988 , vol. 27, # 6 p. 1835 - 1842

16162-69-9

163041-68-7

34221-41-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 11 p. 3320 - 3324

493-33-4

99-93-4

34221-41-5

Literature: Phytochemistry (Elsevier), , vol. 19, p. 2179 - 2184

Precursor 4
18278-34-7 99-93-4 16162-69-9 163041-68-7
DownStream 0

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%