2093386-39-9
2093386-39-9 structure
- Name: Thalidomide-NH-C5-NH2
- Chemical Name: Thalidomide-NH-C5-NH2
- CAS Number: 2093386-39-9
- Molecular Formula: C18H22N4O4
- Molecular Weight: 358.39
- Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
- Create Date: 2021-09-10 18:01:09
- Modify Date: 2024-01-13 15:36:40
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Thalidomide-NH-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
| Name | Thalidomide-NH-C5-NH2 |
|---|
| Description | Thalidomide-NH-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C18H22N4O4 |
|---|---|
| Molecular Weight | 358.39 |