2374122-43-5
2374122-43-5 structure
- Name: PROTAC IRAK4 degrader-3
- Chemical Name: PROTAC IRAK4 degrader-3
- CAS Number: 2374122-43-5
- Molecular Formula: C57H68FN11O8S
- Molecular Weight: 1086.28
- Catalog: Signaling Pathways Immunology/Inflammation IRAK
- Create Date: 2021-09-06 14:49:58
- Modify Date: 2024-01-12 21:48:28
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PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader[1].
| Name | PROTAC IRAK4 degrader-3 |
|---|
| Description | PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader[1]. |
|---|---|
| Related Catalog | |
| Target |
IRAK4 |
| In Vitro | PROTAC IRAK4 degrader-3 (0.01~10 μM; 2 hours; PBMCs) mediated degradation is occurring in a proteasome dependent manner[1]. PROTAC IRAK4 degrader-3 (0.01~100 μM; 18 hours; PBMCs) is capable of completely blocking IL-6 secretion[1]. Western Blot Analysis[1] Cell Line: PBMCs Concentration: 0.01~10 μM Incubation Time: 2 hours Result: IRAK4 PROTAC-mediated degradation was occurring in a proteasome dependent manner. |
| References |
| Molecular Formula | C57H68FN11O8S |
|---|---|
| Molecular Weight | 1086.28 |
| Storage condition | 2-8°C |