55780-30-8
55780-30-8 structure
- Name: Plantanone B
- Chemical Name: Plantanone B
- CAS Number: 55780-30-8
- Molecular Formula: C33H40O20
- Molecular Weight: 756.66
- Catalog: Signaling Pathways Immunology/Inflammation COX
- Create Date: 2021-09-13 20:06:57
- Modify Date: 2025-08-20 11:42:43
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Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research[1].
| Name | Plantanone B |
|---|
| Description | Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research[1]. |
|---|---|
| Related Catalog | |
| Target |
Ovine COX-1:21.78±0.2 μM (IC50) Ovine COX-2:44.01±0.42 μM (IC50) |
| In Vitro | The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM[1]. Plantanone B inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively[1]. .Plantanone B shows significant COX-1 and moderate COX-2 inhibitory activities with IC50 values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively[1]. |
| References |
| Molecular Formula | C33H40O20 |
|---|---|
| Molecular Weight | 756.66 |