2172870-89-0

2172870-89-0 structure

Name: Paltusotine
Chemical Name: Paltusotine
CAS Number: 2172870-89-0
Molecular Formula: C₂₇H₂₂F₂N₄O
Molecular Weight: 456.49
Catalog: Signaling Pathways GPCR/G Protein Somatostatin Receptor
Create Date: 2021-09-05 17:04:32
Modify Date: 2025-08-25 19:57:34
Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist. Paltusotine has the potential for maintaining GH and IGF-1 levels after depot somatostatin receptor ligand therapy[1][2].

Name	Paltusotine

Description	Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist. Paltusotine has the potential for maintaining GH and IGF-1 levels after depot somatostatin receptor ligand therapy[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor Research Areas >> Endocrinology
References	[1]. Murray B. Gordon, et al. Identification of a dose range for once daily oral paltusotine in patients with acromegaly that maintains IGF-1 levels when switching from long-acting somatostatin receptor ligand therapy. Endocrine Abstracts (2021) 73 OC15.4. [2]. Rosa Luo, et al. Pharmacokinetics and Safety of an Improved Oral Formulation of Paltusotine, a Selective, Non-Peptide Somatostatin Receptor 2 (SST2) Agonist for the Treatment of Acromegaly. Journal of the Endocrine Society, Volume 5, Issue Supplement_1, April-May 2021.

Molecular Formula	C₂₇H₂₂F₂N₄O
Molecular Weight	456.49