Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-enenitrile
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: EGFR-IN-16
Price: ￥Inquiry/250mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

133550-22-8

133550-22-8 structure

133550-22-8 structure

Name: EGFR-IN-16
Chemical Name: EGFR-IN-16
CAS Number: 133550-22-8
Molecular Formula: C₁₆H₁₁NO₃
Molecular Weight: 265.26
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2021-09-10 15:58:01
Modify Date: 2025-08-27 17:12:28
EGFR-IN-16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively[1].

Name	EGFR-IN-16

Description	EGFR-IN-16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:4.85 (pIC50) HER2:4.74 (pIC50)
References	[1]. Kamath S, et al. Receptor-guided alignment-based comparative 3D-QSAR studies of benzylidene malonitrile tyrphostins as EGFR and HER-2 kinase inhibitors. J Med Chem. 2003;46(22):4657-4668.

Molecular Formula	C₁₆H₁₁NO₃
Molecular Weight	265.26

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