133550-22-8

133550-22-8 structure
133550-22-8 structure
  • Name: EGFR-IN-16
  • Chemical Name: EGFR-IN-16
  • CAS Number: 133550-22-8
  • Molecular Formula: C16H11NO3
  • Molecular Weight: 265.26
  • Catalog: Signaling Pathways JAK/STAT Signaling EGFR
  • Create Date: 2021-09-10 15:58:01
  • Modify Date: 2025-08-27 17:12:28
  • EGFR-IN-16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively[1].

Name EGFR-IN-16
Description EGFR-IN-16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively[1].
Related Catalog
Target

EGFR:4.85 (pIC50)

HER2:4.74 (pIC50)

References

[1]. Kamath S, et al. Receptor-guided alignment-based comparative 3D-QSAR studies of benzylidene malonitrile tyrphostins as EGFR and HER-2 kinase inhibitors. J Med Chem. 2003;46(22):4657-4668.

Molecular Formula C16H11NO3
Molecular Weight 265.26
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