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934461-40-2

934461-40-2 structure
934461-40-2 structure
  • Name: POT-4
  • Chemical Name: POT-4
  • CAS Number: 934461-40-2
  • Molecular Formula: C72H102N22O18S2
  • Molecular Weight: 1627.85
  • Catalog: Signaling Pathways Immunology/Inflammation Complement System
  • Create Date: 2021-09-13 15:55:58
  • Modify Date: 2024-01-10 19:26:37
  • POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration research[1][2]
Name POT-4
Description POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration research[1][2]
Related Catalog
In Vitro A derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide that exhibits binding activity to C3, preventing cleavage to its active fragments C3a and C3b[2].
References

[1]. S. Kaushal, et al. Complement C3 inhibitor POT-4: Clinical Safety of Intravitreal Administration. ARVO Annual Meeting Abstract, 2009 Apr.

[2]. Robyn Troutbeck, et al. Therapeutic targeting of the complement system in age-related macular degeneration: a review. Clin Exp Ophthalmol. Jan-Feb 2012;40(1):18-26.
Molecular Formula C72H102N22O18S2
Molecular Weight 1627.85

Chemsrc provides CAS#:934461-40-2 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 934461-40-2 | Chemsrc address: https://www.chemsrc.com/en/baike/1681156.html

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