135219-43-1

135219-43-1 structure

Name: poststatin
Chemical Name: N-[(3S)-3-Amino-2-oxopentanoyl]-D-leucyl-N-[(2S,6S)-2,6-diamino-3,7-dimethyl-5-oxooctanoyl]-L-valine
CAS Number: 135219-43-1
Molecular Formula: C₂₆H₄₇N₅O₇
Molecular Weight: 541.681
Catalog: Research Areas Metabolic Disease
Create Date: 2021-09-14 09:59:06
Modify Date: 2025-08-25 14:04:40
Poststatin is a pecific prolyl endopeptidase (PEP) inhibitor. Poststatin inhibits bradykinin-degrading enzymes in rat urine[1][2].

Name	N-[(3S)-3-Amino-2-oxopentanoyl]-D-leucyl-N-[(2S,6S)-2,6-diamino-3,7-dimethyl-5-oxooctanoyl]-L-valine
Synonyms	L-Valine, N-[(3S)-3-amino-1,2-dioxopentyl]-D-leucyl-N-[(2S,6S)-2,6-diamino-3,7-dimethyl-1,5-dioxooctyl]- N-[(3S)-3-Amino-2-oxopentanoyl]-D-leucyl-N-[(2S,6S)-2,6-diamino-3,7-dimethyl-5-oxooctanoyl]-L-valine

Description	Poststatin is a pecific prolyl endopeptidase (PEP) inhibitor. Poststatin inhibits bradykinin-degrading enzymes in rat urine[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. T Aoyagi, et al. Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534-30F3. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1991 Sep;44(9):949-55. [2]. M Majima, et al. Poststatin, a novel inhibitor of bradykinin-degrading enzymes in rat urine. Eur J Pharmacol. 1993 Mar 2;232(2-3):181-90.