24181-66-6

24181-66-6 structure

Name: SIBIRICINE
Chemical Name: (8'R)-8'-Hydroxy-6-methyl-7,8-dihydro-6H-spiro[1,3-dioxolo[4,5-g]isoquinoline-5,7'-indeno[4,5-d][1,3]dioxol]-6'(8'H)-one
CAS Number: 24181-66-6
Molecular Formula: C₂₀H₁₇NO₆
Molecular Weight: 367.352
Catalog: Research Areas Inflammation/Immunology
Create Date: 2021-09-11 18:10:06
Modify Date: 2025-11-25 21:16:58
Sibiricine (Compound 8) is an isoquinoline alkaloid derived from the medicinal plant Corydalis crispa. Sibiricine has significant anti-inflammatory activity on TNF-α production by LPS-activated THP-1 cells[1].

Name	(8'R)-8'-Hydroxy-6-methyl-7,8-dihydro-6H-spiro[1,3-dioxolo[4,5-g]isoquinoline-5,7'-indeno[4,5-d][1,3]dioxol]-6'(8'H)-one
Synonyms	(8'R)-8'-Hydroxy-6-methyl-7,8-dihydro-6H-spiro[1,3-dioxolo[4,5-g]isoquinoline-5,7'-indeno[4,5-d][1,3]dioxol]-6'(8'H)-one Spiro[1,3-dioxolo[4,5-g]isoquinoline-5(6H),7'-[7H]indeno[4,5-d][1,3]dioxol]-6'(8'H)-one, 7,8-dihydro-8'-hydroxy-6-methyl-, (8'R)-

Description	Sibiricine (Compound 8) is an isoquinoline alkaloid derived from the medicinal plant Corydalis crispa. Sibiricine has significant anti-inflammatory activity on TNF-α production by LPS-activated THP-1 cells[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Wangchuk P, et al. Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa. Nat Prod Commun. 2012 May;7(5):575-80.