850786-33-3

850786-33-3 structure

Name: Benzonitrile,4-(4,5-dihydro-1H-imidazol-2-yl)-
Chemical Name: 4-(4,5-Dihydro-1H-imidazol-2-yl)benzonitrile
CAS Number: 850786-33-3
Molecular Formula: C₁₀H₉N₃
Molecular Weight: 171.20
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2021-09-11 08:19:19
Modify Date: 2024-01-06 13:04:37
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule inhibitor of SARS-CoV-2 that targets the main protease (Mpro) of the coronavirus. SARS-CoV-2-IN-59 has a strong interaction with residues on Mpro (Met 165, Gln 166, Met 165, His 41, Gln 189)[1].

Name	4-(4,5-Dihydro-1H-imidazol-2-yl)benzonitrile
Synonyms	MFCD16877945 4-(4,5-Dihydro-1H-imidazol-2-yl)benzonitrile Benzonitrile, 4-(4,5-dihydro-1H-imidazol-2-yl)-

Description	SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule inhibitor of SARS-CoV-2 that targets the main protease (Mpro) of the coronavirus. SARS-CoV-2-IN-59 has a strong interaction with residues on Mpro (Met 165, Gln 166, Met 165, His 41, Gln 189)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	SARS-CoV-2[1]
References	[1]. Azimi S, et al. Green and rapid and instrumental one-pot method for the synthesis of imidazolines having potential anti-SARS-CoV-2 main protease activity. Sustain Chem Pharm. 2023 Sep;34:101136.. .