76265-42-4

76265-42-4 structure
76265-42-4 structure
  • Name: Beauverolide Ka
  • Chemical Name: N-[N-[N-(3-Hydroxy-4-methyl-1-oxodecyl)-L-tryptophyl]-L-phenylalanyl]-D-alloisoleucine λ-lactone
  • CAS Number: 76265-42-4
  • Molecular Formula: C37H50N4O5
  • Molecular Weight: 630.8167
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2021-09-14 00:00:26
  • Modify Date: 2025-08-25 10:00:20
  • Beauverolide Ka, a cyclotetradepsipeptide, is a metabolite of Beauveria bassiana fungus. Beauverolide Ka stimulates glucose uptake in cultured rat L6 myoblasts at 50 μM. Beauverolide Ka exhibits protecting effects on HEI-OC1 cells at 10 μM and shows dose-dependent activity in both L6 myoblasts and myotubes[1][2].

Name N-[N-[N-(3-Hydroxy-4-methyl-1-oxodecyl)-L-tryptophyl]-L-phenylalanyl]-D-alloisoleucine λ-lactone
Description Beauverolide Ka, a cyclotetradepsipeptide, is a metabolite of Beauveria bassiana fungus. Beauverolide Ka stimulates glucose uptake in cultured rat L6 myoblasts at 50 μM. Beauverolide Ka exhibits protecting effects on HEI-OC1 cells at 10 μM and shows dose-dependent activity in both L6 myoblasts and myotubes[1][2].
Related Catalog
Target

Fungal Metabolite

References

[1]. Yuan-Fei Zhou, et al. 3-Hydroxy-4-methyldecanoic Acid-Containing Cyclotetradepsipeptides from an Endolichenic Beauveria sp. J Nat Prod. 2021 Apr 23;84(4):1244-1253.  

[2]. Feifei Luo, et al. Differential metabolic responses of Beauveria bassiana cultured in pupae extracts, root exudates and its interactions with insect and plant. J Invertebr Pathol. 2015 Sep;130:154-64.  

Molecular Formula C37H50N4O5
Molecular Weight 630.8167
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