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  • DC Chemicals Limited
  • China
  • Product Name: PAO-Nap
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1613402-20-2

1613402-20-2 structure
1613402-20-2 structure
  • Name: PAO-Nap
  • Chemical Name: PAO-Nap
  • CAS Number: 1613402-20-2
  • Molecular Formula: C24H24AsN3O5
  • Molecular Weight: 509.39
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2021-09-11 11:35:38
  • Modify Date: 2024-01-02 16:11:12
  • PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase[1].

Name PAO-Nap
Description PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase[1].
Related Catalog
In Vitro PAO exhibits IC50 values of 6.2 μM, 9.4 μM, 7.7 μM in HL-60, 7721 and Hela cells (48 h)[1].
References

[1]. Yaping Liu, et al. Dithiaarsanes induce oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase. J Med Chem. 2014 Jun 26;57(12):5203-11.

Molecular Formula C24H24AsN3O5
Molecular Weight 509.39