Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PAO-Nap
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: PAO-Nap
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1613402-20-2

1613402-20-2 structure

1613402-20-2 structure

Name: PAO-Nap
Chemical Name: PAO-Nap
CAS Number: 1613402-20-2
Molecular Formula: C₂₄H₂₄AsN₃O₅
Molecular Weight: 509.39
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2021-09-11 11:35:38
Modify Date: 2024-01-02 16:11:12
PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase[1].

Name	PAO-Nap

Description	PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	PAO exhibits IC50 values of 6.2 μM, 9.4 μM, 7.7 μM in HL-60, 7721 and Hela cells (48 h)[1].
References	[1]. Yaping Liu, et al. Dithiaarsanes induce oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase. J Med Chem. 2014 Jun 26;57(12):5203-11.

Molecular Formula	C₂₄H₂₄AsN₃O₅
Molecular Weight	509.39

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