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2250056-27-8

2250056-27-8 structure
2250056-27-8 structure
  • Name: HO-PEG7-CH2COOH
  • Chemical Name: HO-PEG7-CH2COOH
  • CAS Number: 2250056-27-8
  • Molecular Formula: C16H32O10
  • Molecular Weight: 384.42
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-13 21:03:53
  • Modify Date: 2024-01-17 09:48:03
  • HO-PEG7-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name HO-PEG7-CH2COOH
Description HO-PEG7-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H32O10
Molecular Weight 384.42