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2428400-07-9

2428400-07-9 structure
2428400-07-9 structure
  • Name: Amino-PEG7-t-butyl ester
  • Chemical Name: Amino-PEG7-t-butyl ester
  • CAS Number: 2428400-07-9
  • Molecular Formula: C21H43NO9
  • Molecular Weight: 453.57
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-10 22:27:49
  • Modify Date: 2024-01-12 14:03:57
  • Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Amino-PEG7-t-butyl ester
Synonyms MFCD32861276
Description Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C21H43NO9
Molecular Weight 453.57