80152-07-4

80152-07-4 structure

Name: Streptazolin
Chemical Name: Streptazolin
CAS Number: 80152-07-4
Molecular Formula: C₁₁H₁₃NO₃
Molecular Weight: 207.226
Catalog: Research Areas Infection
Create Date: 2021-09-16 19:22:36
Modify Date: 2025-08-25 09:37:02
Streptazolin is an antibiotic. Streptazolin increases bacterial killing and elaboration of immunostimulatory cytokines by macrophages in vitro. Streptazolin stimulates the macrophage NF-κB pathway via PI3K signaling[1][2].

Name	Streptazolin
Synonyms	1H-2-Oxa-7a-azacyclopent[cd]inden-1-one, 4-ethylidene-2a,3,4,6,7,7b-hexahydro-3-hydroxy-, (2aS,3S,4Z,7bS)- (+)-streptazolin streptazolin (2aS,3S,4Z,7bS)-4-Ethylidene-3-hydroxy-2a,3,4,6,7,7b-hexahydro-2-oxa-7a-azacyclopenta[cd]inden-1-one

Description	Streptazolin is an antibiotic. Streptazolin increases bacterial killing and elaboration of immunostimulatory cytokines by macrophages in vitro. Streptazolin stimulates the macrophage NF-κB pathway via PI3K signaling[1][2].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology
References	[1]. Groenhagen U, et al. Streptopyridines, volatile pyridine alkaloids produced by Streptomyces sp. FORM5. Beilstein J Org Chem. 2014;10:1421-1432. Published 2014 Jun 24. [2]. Perry JA, et al. A macrophage-stimulating compound from a screen of microbial natural products. J Antibiot (Tokyo). 2015;68(1):40-46.