182135-66-6

182135-66-6 structure

182135-66-6 structure

Name: BMS-195614
Chemical Name: BMS 195614
CAS Number: 182135-66-6
Molecular Formula: C₂₉H₂₄N₂O₃
Molecular Weight: 448.51
Catalog: Signaling Pathways Metabolic Enzyme/Protease RAR/RXR
Create Date: 2021-07-10 10:55:25
Modify Date: 2023-01-14 18:29:09
BMS-195614 (BMS 614) is a neutral RARα-selective antagonist with a Ki of 2.5 nM[1].

Name	BMS 195614
Synonyms	BMS 614 BMS614 BMS 195614 BMS-614 4-[[[5,6-Dhydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]-benzoic acid MFCD00952209 BMS195614 BMS-195614 4-({[5,5-Dimethyl-8-(3-quinolinyl)-5,6-dihydro-2-naphthalenyl]carbonyl}amino)benzoic acid 4-[5,6-Dihydro-5,5-dimethyl-8-(quinolin-3-yl)naphthalen-2-carboxamido] benzoic acid Benzoic acid, 4-[[[5,6-dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]-

Description	BMS-195614 (BMS 614) is a neutral RARα-selective antagonist with a Ki of 2.5 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR
References	[1]. Géhin M, et al. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem Biol. 1999;6(8):519-529.

Density	1.3±0.1 g/cm3
Boiling Point	607.3±55.0 °C at 760 mmHg
Molecular Formula	C₂₉H₂₄N₂O₃
Molecular Weight	448.51
Flash Point	321.1±31.5 °C
Exact Mass	448.178680
LogP	7.05
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.693

RIDADR	NONH for all modes of transport