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13879-04-4

13879-04-4 structure
13879-04-4 structure
  • Name: Euphol Acetate
  • Chemical Name: Euphol Acetate
  • CAS Number: 13879-04-4
  • Molecular Formula: C32H52O2
  • Molecular Weight: 468.75
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2021-06-18 19:51:40
  • Modify Date: 2024-01-16 05:35:50
  • Euphol acetate is a triterpene that can be isolated from Euphorbia broteri. Euphol acetate is an inhibitor of hepatic transport proteins organic anion-transporting polypeptide 1/3 (OATP1B1/3)[1][2].

Name Euphol Acetate
Description Euphol acetate is a triterpene that can be isolated from Euphorbia broteri. Euphol acetate is an inhibitor of hepatic transport proteins organic anion-transporting polypeptide 1/3 (OATP1B1/3)[1][2].
Related Catalog
Target

OATP1B1/3[2]

In Vitro Euphol acetate (10μM) suppresses the uptake of the OATP1B substrate sodium fluorescein in OATP1B1 (29.2%)- or 1B3 (40.2%)-transfected CHO cells[2].
References

[1]. DePascual Teresa, et al. Triterpenes from Euphorbia broteri. Phytochemistry. 1987. 26(6): 1767-1776.

[2]. Tom De Bruyn, et al. Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol. 2013 Jun;83(6):1257-67.

Molecular Formula C32H52O2
Molecular Weight 468.75