1007476-63-2

1007476-63-2 structure

Name: MJ33 lithium salt
Chemical Name: MJ33 (lithium salt)
CAS Number: 1007476-63-2
Molecular Formula: C₂₂H₄₃F₃LiO₆P
Molecular Weight: 498.483
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phospholipase
Create Date: 2021-04-30 12:06:26
Modify Date: 2024-01-05 11:18:24
MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6[1].

Name	MJ33 (lithium salt)
Synonyms	MJ33 lithium salt 1-Hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol lithium Lithium 1-(hexadecyloxy)-3-(2,2,2-trifluoroethoxy)-2-propanyl methyl phosphate MFCD03787978 Phosphoric acid, 2-(hexadecyloxy)-1-[(2,2,2-trifluoroethoxy)methyl]ethyl methyl ester, lithium salt (1:1)

Description	MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Metabolic Disease
References	[1]. Fisher AB, Dodia C, Chander A, Jain M. A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung. Biochem J. 1992 Dec 1;288 ( Pt 2)(Pt 2):407-11.