218464-59-6
218464-59-6 structure
- Name: VPC-13566
- Chemical Name: VPC-13566
- CAS Number: 218464-59-6
- Molecular Formula: C18H14N2
- Molecular Weight: 258.32
- Catalog: Research Areas Cancer
- Create Date: 2021-01-08 16:29:54
- Modify Date: 2024-04-01 20:46:21
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VPC-13566 is an advanced BF3-specific small molecule that was previously reported to effectively inhibit AR transcriptional activity and to displace the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines, including an enzalutamide-resistant cell line, and reduces the growth of AR-dependent prostate cancer xenograft tumors in mice.
| Name | VPC-13566 |
|---|
| Description | VPC-13566 is an advanced BF3-specific small molecule that was previously reported to effectively inhibit AR transcriptional activity and to displace the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines, including an enzalutamide-resistant cell line, and reduces the growth of AR-dependent prostate cancer xenograft tumors in mice. |
|---|
| Molecular Formula | C18H14N2 |
|---|---|
| Molecular Weight | 258.32 |