358375-11-8

358375-11-8 structure

Name: GKK1032B
Chemical Name: GKK1032B
CAS Number: 358375-11-8
Molecular Formula: C₃₂H₃₉NO₄
Molecular Weight: 501.656
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2021-01-08 06:33:09
Modify Date: 2024-01-30 17:23:28
GKK1032B is an alkaloid compound that can be found in endophytic fungus Penicillium sp. GKK1032B can induce the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation[1].

Name	GKK1032B
Synonyms	5,8-Ethenofluoreno[9',1':2,3,4]oxacyclododecino[6,7-c]pyrrole-1,3,17(2H,4H,10H)-trione, 16-ethenyl-3a,9a,9b,11,12,13,13a,13b,16,16a,16b,17a-dodecahydro-10,12,13a,14,16-pentamethyl-, (3aS,9aS,9bR,10S,12R,13aS,13bS,16S,16aR,16bS,17aR)- GKK1032B (3S,4R,5S,7R,9S,10S,13S,14R,16R,20S,27S)-5,7,9,11,13-Pentamethyl-13-vinyl-2-oxa-18-azahexacyclo[20.2.2.13,10.04,9.014,27.016,20]heptacosa-1(24),11,22,25-tetraene-15,17,19-trione

Description	GKK1032B is an alkaloid compound that can be found in endophytic fungus Penicillium sp. GKK1032B can induce the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Qi X, et, al. GKK1032C, a new alkaloid compound from the endophytic fungus Penicillium sp. CPCC 400817 with activity against methicillin-resistant S. aureus. J Antibiot (Tokyo). 2019 Apr;72(4):237-240. [2]. Liu N, et, al. GKK1032B from endophytic Penicillium citrinum induces the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation. Chin J Nat Med. 2022 Jan;20(1):67-73.