1613465-33-0

1613465-33-0 structure

Name: ML336
Chemical Name: ML-336
CAS Number: 1613465-33-0
Molecular Formula: C₁₉H₂₁N₅O₃
Molecular Weight: 367.402
Catalog: Research Areas Infection
Create Date: 2021-01-12 13:24:44
Modify Date: 2024-04-09 15:46:28
ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range[1].

Name	ML-336
Synonyms	ML-336 MFCD28160682 Benzamide, 2-[[(2E)-1,4-dimethyl-2-piperazinylidene]amino]-5-nitro-N-phenyl- 2-[(E)-(1,4-Dimethyl-2-piperazinylidene)amino]-5-nitro-N-phenylbenzamide

Description	ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range[1].
Related Catalog	Research Areas >> Infection
References	[1]. Chung D, et al. ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV). 2012 Dec 17 [updated 2013 Nov 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. [2]. Donghoon Chung 1, et al. ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV).