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299946-20-6

299946-20-6 structure
299946-20-6 structure
  • Name: Bax BH3 peptide (55-74), wild type
  • Chemical Name: Bax BH3 peptide (55-74), wild type
  • CAS Number: 299946-20-6
  • Molecular Formula: C93H163N27O34S2
  • Molecular Weight: 2267.60
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2021-01-19 15:53:30
  • Modify Date: 2024-01-05 20:13:56
  • Bax BH3 peptide (55-74), wild type is a 20-amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models[1].

Name Bax BH3 peptide (55-74), wild type
Description Bax BH3 peptide (55-74), wild type is a 20-amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models[1].
Related Catalog
In Vitro In addition to disrupting Bax/Bcl-2 and Bax/Bcl-XL, Bax BH3 peptide (55-74), wild type can promote cytochrome c release from isolated mitochondria. Bax BH3 belongs to the Bcl-2 protein family which consists of both pro-apoptotic and anti-apoptotic members. Bax BH3 acts to regulate apoptosis via governance of the 'intrinsic' pathway of cell death[1].
References

[1]. Peter E Czabotar, et al. Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis. J Biol Chem. 2011 Mar 4;286(9):7123-31.

Molecular Formula C93H163N27O34S2
Molecular Weight 2267.60