1379577-47-5

1379577-47-5 structure

Name: Puwainaphycin F
Chemical Name: Puwainaphycin F
CAS Number: 1379577-47-5
Molecular Formula: C₅₃H₈₇N₁₃O₁₅
Molecular Weight: 1146.34
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
Create Date: 2020-08-07 18:42:40
Modify Date: 2024-01-11 16:54:02
Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization[1].

Name	Puwainaphycin F

Description	Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
In Vitro	Puwainaphycin F has an IC50 of 2.19 μM in HeLa cells[1].
References	[1]. Pavel Hrouzek , et al. The cyanobacterial cyclic lipopeptides puwainaphycins F/G are inducing necrosis via cell membrane permeabilization and subsequent unusual actin relocalization. Chem Res Toxicol. 2012 Jun 18;25(6):1203-11.

Molecular Formula	C₅₃H₈₇N₁₃O₁₅
Molecular Weight	1146.34