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2414374-41-5

2414374-41-5 structure
2414374-41-5 structure
  • Name: EMI56
  • Chemical Name: EMI56
  • CAS Number: 2414374-41-5
  • Molecular Formula: C21H20N2O3
  • Molecular Weight: 348.40
  • Catalog: Signaling Pathways JAK/STAT Signaling EGFR
  • Create Date: 2020-08-10 20:31:33
  • Modify Date: 2024-01-02 10:37:04
  • EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants[1].

Name EMI56
Description EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants[1].
Related Catalog
Target

EGFRL858R/T790M/C797S

EGFRdel19 T790M C797S

In Vitro EMI56 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI56 can be used in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC)[1].
References

[1]. Punit Saraon , et al. A Drug Discovery Platform to Identify Compounds That Inhibit EGFR Triple Mutants.Nat Chem Biol. 2020 May;16(5):577-586.

Molecular Formula C21H20N2O3
Molecular Weight 348.40
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