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720707-93-7

720707-93-7 structure
720707-93-7 structure

Name Tetraethyl butane-​1,​4-​diylbis(phosphoramid​ate)
Synonyms MFCD25424110
Description Tetraethyl butane-​1,​4-​diylbis(phosphoramid​ate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H30N2O6P2
Molecular Weight 360.32
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