2055024-37-6

2055024-37-6 structure

2055024-37-6 structure

Name: Acid-PEG4-Sulfone-PEG4-acid
Chemical Name: Sulfone-Bis-PEG4-acid
CAS Number: 2055024-37-6
Molecular Formula: C₂₂H₄₂O₁₄S
Molecular Weight: 562.63
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:49:12
Modify Date: 2024-01-02 17:39:49
Sulfone-Bis-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Sulfone-Bis-PEG4-acid

Description	Sulfone-Bis-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₂H₄₂O₁₄S
Molecular Weight	562.63