2172820-09-4

2172820-09-4 structure

2172820-09-4 structure

Name: (S,R,S)-AHPC-PEG2-acid
Chemical Name: (S,R,S)-AHPC-PEG2-acid
CAS Number: 2172820-09-4
Molecular Formula: C₃₀H₄₂N₄O₈S
Molecular Weight: 618.74
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 09:18:01
Modify Date: 2024-01-22 19:18:18
(S,R,S)-AHPC-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	(S,R,S)-AHPC-PEG2-acid
Synonyms	MFCD32670313

Description	(S,R,S)-AHPC-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₀H₄₂N₄O₈S
Molecular Weight	618.74