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2055014-77-0

2055014-77-0 structure
2055014-77-0 structure
  • Name: N-Me-N-(PEG4-acid)2
  • Chemical Name: N-Me-N-bis(PEG4-acid)
  • CAS Number: 2055014-77-0
  • Molecular Formula: C23H45NO12
  • Molecular Weight: 527.60
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:26:50
  • Modify Date: 2024-01-08 20:08:58
  • N-Me-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-Me-N-bis(PEG4-acid)
Synonyms MFCD28976691
Description N-Me-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C23H45NO12
Molecular Weight 527.60