2204309-09-9

2204309-09-9 structure
2204309-09-9 structure
  • Name: Mal-PEG4-Glu(OH)-NH-m-PEG24
  • Chemical Name: Mal-PEG4-Glu(OH)-NH-m-PEG24
  • CAS Number: 2204309-09-9
  • Molecular Formula: C72H134N4O35
  • Molecular Weight: 1615.84
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 22:16:13
  • Modify Date: 2024-01-02 07:37:29
  • Mal-PEG4-Glu(OH)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG4-Glu(OH)-NH-m-PEG24
Synonyms MFCD28505508
Description Mal-PEG4-Glu(OH)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C72H134N4O35
Molecular Weight 1615.84