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2253965-15-8

2253965-15-8 structure
2253965-15-8 structure
  • Name: Mal-amide-PEG2-oxyamine-Boc
  • Chemical Name: Mal-amide-PEG2-oxyamine-Boc
  • CAS Number: 2253965-15-8
  • Molecular Formula: C18H29N3O8
  • Molecular Weight: 415.44
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:33:46
  • Modify Date: 2024-01-09 18:35:29
  • Mal-amide-PEG2-oxyamineBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-amide-PEG2-oxyamine-Boc
Description Mal-amide-PEG2-oxyamineBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C18H29N3O8
Molecular Weight 415.44