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66722-87-0

66722-87-0 structure
66722-87-0 structure
  • Name: m-PEG3-acid chloride
  • Chemical Name: m-PEG3-Propanoyl chloride
  • CAS Number: 66722-87-0
  • Molecular Formula: C8H15ClO4
  • Molecular Weight: 210.66
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 16:05:15
  • Modify Date: 2024-01-07 19:10:03
  • m-PEG3-Propanoyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG3-Propanoyl chloride
Synonyms MFCD30182064
Description m-PEG3-Propanoyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C8H15ClO4
Molecular Weight 210.66