1949843-39-3

1949843-39-3 structure

1949843-39-3 structure

Name: m-PEG12-NH-C2-acid
Chemical Name: m-PEG12-NH-C2-acid
CAS Number: 1949843-39-3
Molecular Formula: C₂₈H₅₇NO₁₄
Molecular Weight: 631.75
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 15:32:07
Modify Date: 2024-01-03 14:08:19
m-PEG12-NH-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG12-NH-C2-acid

Description	m-PEG12-NH-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₈H₅₇NO₁₄
Molecular Weight	631.75