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1608140-48-2

1608140-48-2 structure
1608140-48-2 structure
  • Name: endo-BCN-PEG8-NHS ester
  • Chemical Name: endo-BCN-PEG8-NHS ester
  • CAS Number: 1608140-48-2
  • Molecular Formula: C34H54N2O14
  • Molecular Weight: 714.80
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:45:27
  • Modify Date: 2024-04-06 17:26:45
  • endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name endo-BCN-PEG8-NHS ester
Synonyms MFCD31692212
Description endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C34H54N2O14
Molecular Weight 714.80