2112737-93-4

2112737-93-4 structure

2112737-93-4 structure

Name: DSPE-PEG5-propargyl
Chemical Name: DSPE-PEG5-propargyl
CAS Number: 2112737-93-4
Molecular Formula: C₅₅H₁₀₄NO₁₄P
Molecular Weight: 1034.39
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:19:11
Modify Date: 2024-01-17 18:42:03
DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DSPE-PEG5-propargyl

Description	DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₅₅H₁₀₄NO₁₄P
Molecular Weight	1034.39