2032788-37-5

2032788-37-5 structure

Name: Desthiobiotin-PEG4-DBCO
Chemical Name: DBCO-PEG4-Desthiobiotin
CAS Number: 2032788-37-5
Molecular Formula: C₃₉H₅₃N₅O₈
Molecular Weight: 719.87
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:08:09
Modify Date: 2025-08-26 18:39:28
DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG4-Desthiobiotin

Description	DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562