2375193-74-9

2375193-74-9 structure
2375193-74-9 structure
  • Name: DBCO-NH-(CH2)4COOH
  • Chemical Name: DBCO-NH-(CH2)4COOH
  • CAS Number: 2375193-74-9
  • Molecular Formula: C24H24N2O4
  • Molecular Weight: 404.46
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:22:15
  • Modify Date: 2024-01-31 00:15:29
  • DBCO-NH-(CH2)4COOH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DBCO-NH-(CH2)4COOH
Description DBCO-NH-(CH2)4COOH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C24H24N2O4
Molecular Weight 404.46