1803279-86-8

1803279-86-8 structure
1803279-86-8 structure
  • Name: DBCO-C2-SulfoNHS ester
  • Chemical Name: DBCO-C2-SulfoNHS ester
  • CAS Number: 1803279-86-8
  • Molecular Formula: C23H18N2O8S
  • Molecular Weight: 482.46
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:41:32
  • Modify Date: 2024-01-14 15:01:21
  • DBCO-C2-SulfoNHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DBCO-C2-SulfoNHS ester
Description DBCO-C2-SulfoNHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C23H18N2O8S
Molecular Weight 482.46
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