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959245-08-0

959245-08-0 structure
959245-08-0 structure
  • Name: CBS1117
  • Chemical Name: CBS1117
  • CAS Number: 959245-08-0
  • Molecular Formula: C15H20Cl2N2O
  • Molecular Weight: 315.24
  • Catalog: Signaling Pathways Anti-infection Influenza Virus
  • Create Date: 2020-06-01 17:52:09
  • Modify Date: 2024-01-17 21:50:54
  • CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A viruses, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process[1].

Name CBS1117
Description CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A viruses, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process[1].
Related Catalog
Target

IC50: 70 nM (H1N1)[1]

In Vitro CBS1117 has a lower IC50 value of 70 nM and higher CC50 value of 274 μM, leading to an excellent antiviral selectivity index value (SI value of 3914) in human lung epithelial cell line (A549)[1].
References

[1]. Hussein AFA, et al. Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus. Antiviral Res. 2020 May;177:104782.

Molecular Formula C15H20Cl2N2O
Molecular Weight 315.24