1292268-14-4

1292268-14-4 structure

1292268-14-4 structure

Name: 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-yl 4-methylbenzenesulfonate
Chemical Name: Boc-NH-PEG7-Tos
CAS Number: 1292268-14-4
Molecular Formula: C₂₆H₄₅NO₁₁S
Molecular Weight: 579.70
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 21:56:02
Modify Date: 2024-01-10 17:02:46
Boc-NH-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-NH-PEG7-Tos

Description	Boc-NH-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₆H₄₅NO₁₁S
Molecular Weight	579.70